Decentralized
Study of
Celiprolol on
vEDS-related
Event
Reduction
Zevra Therapeutics plans to conduct a clinical trial in the U.S. to evaluate the efficacy of a medicine known as celiprolol for the treatment of vascular Ehlers-Danlos Syndrome (vEDS).
Objective
The study is being planned to evaluate males and females who have a confirmed diagnosis of vEDS by a COL3A1 mutation verified by genetic testing.
As planning for the trial progresses, we are actively looking for potential participants with a confirmed diagnosis of vEDS who are interested in participating in this investigational trial.
As with any clinical study, participation will be subject to a number of inclusion and exclusion criteria.
About Celiprolol
Celiprolol is an investigational product and the safety and efficacy has not been established.
There is no guarantee that celiprolol will receive health authority approval or become commercially available for vEDS in the U.S.
Inclusion Criteria:
To pre-qualify for this clinical research study, you must meet the following criteria:
Please note this is a summary of the main criteria to assess pre-eligibility and is not an exhaustive list
20 November 2023 - Acer Therapeutics acquired by Zevra Therapeutics.
Click here
to read the announcement. Enrollment for the trial is currently paused.
Update on the upcoming VEDS Clinical Trial in the US regarding Celiprolol: Acer Therapeutics’ EDSIVO™ (celiprolol) Granted FDA Breakthrough Therapy Designation for vascular Ehlers-Danlos Syndrome.
Acer Therapeutics, a pharmaceutical company focused on the acquisition, development and commercialization of therapies for serious rare and life-threatening diseases with significant unmet medical needs, announced the U.S. Food and Drug Administration (FDA) has granted celiprolol Breakthrough Therapy designation (BTD) in the U.S. for the treatment of patients with COL3A1-positive vascular Ehlers-Danlos syndrome (vEDS).